![]() Scaffolds with compressive strengths comparable to those of trabecular and cortical bones have been produced by a variety of methods. The review reveals the fact that mechanical strength is not a real limiting factor in the use of bioactive glass scaffolds for bone repair, an observation not often recognized by most researchers and clinicians. This paper provides an overview of recent developments in the fabrication and mechanical properties of bioactive glass scaffolds. Bioactive glass has appealing characteristics as a scaffold material for bone tissue engineering, but the application of glass scaffolds for the repair of load-bearing bone defects is often limited by their low mechanical strength and fracture toughness. The repair and regeneration of large bone defects resulting from disease or trauma remains a significant clinical challenge.
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